Nalidixic acid

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Nalidixic acid Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCN1c2nc(C)ccc2C(=O)C2(C(=O)O)OC12 N-Dealkylation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCNc1nc(C)ccc1C(=O)C1(C(=O)O)OC1O UGT Conjugation prediction

Generation 3

Select a metabolite to form the next generation.