Substrate
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Generation 1
XenoSite
Troglitazone
Cc1c(C)c2c(c(C)c1O)CCC(C)(COc1ccc(CC3SC(=O)NC3=O)cc1)O2
CHEBI
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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Generation 1
Show metabolites
C=C1C(=O)C(C)=C(C)C2=C1CCC(C)(COc1ccc(CC3SC(=O)NC3=O)cc1)O2
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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gsh
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protein
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cyanide
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dna
Generation 2
Select a metabolite to form the next generation.
glutathionation
Probability 0.68
0.68
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protein
Probability 0.63
0.63
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dna
Probability 0.39
0.39
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cyanide
Probability 0.00
0.00
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