Aristolochic acid a

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Aristolochic acid a Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

COc1cccc2c3c(c([N+](=O)[O-])cc12)C(C(=O)O)=CC(=O)C3=O UGT Conjugation prediction

Generation 2

Select a metabolite to form the next generation.

glucuronidation
1.00