Aripiprazole

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Aripiprazole Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCN(CCCCOc1ccc2c(c1)NC(=O)CC2)CCN=C1C=CC(=O)C(Cl)=C1Cl Epoxidation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCN(CCCCOC12C=C3NC(=O)CCC3=CC1O2)CCN=C1C=CC(=O)C(Cl)=C1Cl gsh prediction

CCN(CCCCOC12C=C3NC(=O)CCC3=CC1O2)CCN=C1C=CC(=O)C(Cl)=C1Cl protein prediction

CCN(CCCCOC12C=C3NC(=O)CCC3=CC1O2)CCN=C1C=CC(=O)C(Cl)=C1Cl cyanide prediction

CCN(CCCCOC12C=C3NC(=O)CCC3=CC1O2)CCN=C1C=CC(=O)C(Cl)=C1Cl dna prediction

Generation 3

Select a metabolite to form the next generation.

Showing 5 of 24 metabolites