Arenamide a

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Arenamide a Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCCCCCC(C)C1CC(=O)NCC(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CC2=CC=CC(=O)C2=O)C(=O)O1 N-Dealkylation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCCCCCC(C)C(CC(=O)NCC(=O)NC(C(=O)NC(CC(C)C)C(N)=O)C(C)C)OC(=O)C(CC1=CC=CC(=O)C1=O)NC(=O)C(C)=O Epoxidation prediction

Generation 3

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCCCCCC(C)C(CC(=O)NCC(=O)NC(C(=O)NC(CC(C)C)C(N)=O)C(C)C)OC(=O)C(CC12OC1C=CC(=O)C2=O)NC(=O)C(C)=O stable oxygenation prediction

CCCCCCC(C)C(CC(=O)NCC(=O)NC(C(=O)NC(CC(C)C)C(N)=O)C(C)C)OC(=O)C(CC12OC1C=CC(=O)C2=O)NC(=O)C(C)=O unstable oxygenation prediction

CCCCCCC(C)C(CC(=O)NCC(=O)NC(C(=O)NC(CC(C)C)C(N)=O)C(C)C)OC(=O)C(CC12OC1C=CC(=O)C2=O)NC(=O)C(C)=O dehydrogenation prediction

CCCCCCC(C)C(CC(=O)NCC(=O)NC(C(=O)NC(CC(C)C)C(N)=O)C(C)C)OC(=O)C(CC12OC1C=CC(=O)C2=O)NC(=O)C(C)=O reduction prediction

CCCCCCC(C)C(CC(=O)NCC(=O)NC(C(=O)NC(CC(C)C)C(N)=O)C(C)C)OC(=O)C(CC12OC1C=CC(=O)C2=O)NC(=O)C(C)=O hydrolysis prediction

Generation 4

Select a metabolite to form the next generation.

Showing 5 of 237 metabolites