Tenofovir

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Tenofovir Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CC(C[N+]1=c2ncnc(N)c2=NC1=O)OCP(=O)(O)O N-Dealkylation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CC(CO)OCP(=O)(O)O gsh prediction

CC(CO)OCP(=O)(O)O protein prediction

CC(CO)OCP(=O)(O)O cyanide prediction

CC(CO)OCP(=O)(O)O dna prediction