Tenofovir

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Tenofovir Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CC(C[N+]1=c2ncnc(N)c2=NC1=O)OCP(=O)(O)O N-Dealkylation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CC(C[N+](C(=O)O)=C1N=CN=C(N)C1=N)OCP(=O)(O)O Epoxidation prediction

Generation 3

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CC(C[N+](C(=O)O)=C1N=CN=C(N)C12NO2)OCP(=O)(O)O stable oxygenation prediction

CC(C[N+](C(=O)O)=C1N=CN=C(N)C12NO2)OCP(=O)(O)O unstable oxygenation prediction

CC(C[N+](C(=O)O)=C1N=CN=C(N)C12NO2)OCP(=O)(O)O dehydrogenation prediction

CC(C[N+](C(=O)O)=C1N=CN=C(N)C12NO2)OCP(=O)(O)O reduction prediction

CC(C[N+](C(=O)O)=C1N=CN=C(N)C12NO2)OCP(=O)(O)O hydrolysis prediction

Generation 4

Select a metabolite to form the next generation.

Showing 5 of 84 metabolites