Amrinone

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Amrinone Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Nc1cc(C2=CC=NC(=O)C2=O)c[nH]c1=O Epoxidation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Nc1cc(C2=CC3ON3C(=O)C2=O)c[nH]c1=O N-Dealkylation prediction

Generation 3

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Nc1cc(C(=CC2NO2)C(=O)C(=O)O)c[nH]c1=O UGT Conjugation prediction

Generation 4

Select a metabolite to form the next generation.

glucuronidation
0.92