Amrinone

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Amrinone Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NC1=CC(=C2C=CN=CC2=O)C(=O)NC1=O N-Dealkylation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NC(=O)C(N)=CC(C(=O)O)=C1C=CN=CC1=O gsh prediction

NC(=O)C(N)=CC(C(=O)O)=C1C=CN=CC1=O protein prediction

NC(=O)C(N)=CC(C(=O)O)=C1C=CN=CC1=O cyanide prediction

NC(=O)C(N)=CC(C(=O)O)=C1C=CN=CC1=O dna prediction

Generation 3

Select a metabolite to form the next generation.