Amrinone

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Amrinone Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=C1C=C(c2ccncc2)C(=O)NC1=O N-Dealkylation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=C(C=C(C(=O)O)c1ccncc1)C(N)=O gsh prediction

N=C(C=C(C(=O)O)c1ccncc1)C(N)=O protein prediction

N=C(C=C(C(=O)O)c1ccncc1)C(N)=O cyanide prediction

N=C(C=C(C(=O)O)c1ccncc1)C(N)=O dna prediction

Generation 3

Select a metabolite to form the next generation.