Amperozide cation

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Amperozide cation Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCNC(=O)N1CC[NH+](CCCC(=C2C=CC(F)=CC2=O)c2ccc(F)cc2)CC1 Epoxidation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCNC(=O)N1CC[NH+](CCCC(=C2C(=O)C=C(F)C3OC23)c2ccc(F)cc2)CC1 stable oxygenation prediction

CCNC(=O)N1CC[NH+](CCCC(=C2C(=O)C=C(F)C3OC23)c2ccc(F)cc2)CC1 unstable oxygenation prediction

CCNC(=O)N1CC[NH+](CCCC(=C2C(=O)C=C(F)C3OC23)c2ccc(F)cc2)CC1 dehydrogenation prediction

CCNC(=O)N1CC[NH+](CCCC(=C2C(=O)C=C(F)C3OC23)c2ccc(F)cc2)CC1 reduction prediction

CCNC(=O)N1CC[NH+](CCCC(=C2C(=O)C=C(F)C3OC23)c2ccc(F)cc2)CC1 hydrolysis prediction

Generation 3

Select a metabolite to form the next generation.

Showing 5 of 134 metabolites