Amp morpholidate

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Amp morpholidate Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NC1=NC(=O)N=C2C1=NC(=O)N2C1OC(COP(=O)(O)N2CCOCC2)C(O)C1O stable oxygenation prediction

NC1=NC(=O)N=C2C1=NC(=O)N2C1OC(COP(=O)(O)N2CCOCC2)C(O)C1O unstable oxygenation prediction

NC1=NC(=O)N=C2C1=NC(=O)N2C1OC(COP(=O)(O)N2CCOCC2)C(O)C1O dehydrogenation prediction

NC1=NC(=O)N=C2C1=NC(=O)N2C1OC(COP(=O)(O)N2CCOCC2)C(O)C1O reduction prediction

NC1=NC(=O)N=C2C1=NC(=O)N2C1OC(COP(=O)(O)N2CCOCC2)C(O)C1O hydrolysis prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NC1=NC(=O)N=C2NC(=O)N=C12 N-Dealkylation prediction

Generation 3

Select a metabolite to form the next generation.

Showing 5 of 7 metabolites