Substrate
Generation 1

Abacavir carboxylate

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Abacavir carboxylate Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Nc1nc(NC2CC2)c2c(n1)=[N+](C1C=CC(C(=O)O)C1)C(=O)N=2 gsh prediction

Nc1nc(NC2CC2)c2c(n1)=[N+](C1C=CC(C(=O)O)C1)C(=O)N=2 protein prediction

Nc1nc(NC2CC2)c2c(n1)=[N+](C1C=CC(C(=O)O)C1)C(=O)N=2 cyanide prediction

Nc1nc(NC2CC2)c2c(n1)=[N+](C1C=CC(C(=O)O)C1)C(=O)N=2 dna prediction