Substrate
Generation 1

Monoacetyldapsone

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Monoacetyldapsone stable oxygenation prediction

Monoacetyldapsone unstable oxygenation prediction

Monoacetyldapsone dehydrogenation prediction

Monoacetyldapsone reduction prediction

Monoacetyldapsone hydrolysis prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CC(=O)Nc1ccc(S(=O)(=O)c2ccc(N=O)cc2)cc1 UGT Conjugation prediction