Substrate
/
Generation 1
XenoSite
Diclofenac
O=C(O)Cc1ccccc1Nc1c(Cl)cccc1Cl
CHEBI
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Description
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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stable oxygenation
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unstable oxygenation
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dehydrogenation
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reduction
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hydrolysis
Generation 1
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(o-(2,6-dichloro-4-hydroxyanilino)phenyl)acetic acid
O=C(O)Cc1ccccc1Nc1c(Cl)cc(O)cc1Cl
CHEBI
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Description
▾
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
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Generation 2
Select a metabolite to form the next generation.
glucuronidation
Probability 0.68
0.68
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glucuronidation
Probability 0.53
0.53
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