Substrate
Generation 1

Azathymidine

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azathymidine stable oxygenation prediction

Azathymidine unstable oxygenation prediction

Azathymidine dehydrogenation prediction

Azathymidine reduction prediction

Azathymidine hydrolysis prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)nc1CO Quinonation prediction