Substrate
Generation 1

Arisugacin c

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Arisugacin c stable oxygenation prediction

Arisugacin c unstable oxygenation prediction

Arisugacin c dehydrogenation prediction

Arisugacin c reduction prediction

Arisugacin c hydrolysis prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CC12CCC3(O)C(C)(C)C(=O)CCC3(C)C1Cc1c(cc(-c3ccc(O)cc3)oc1=O)O2 gsh prediction

CC12CCC3(O)C(C)(C)C(=O)CCC3(C)C1Cc1c(cc(-c3ccc(O)cc3)oc1=O)O2 protein prediction

CC12CCC3(O)C(C)(C)C(=O)CCC3(C)C1Cc1c(cc(-c3ccc(O)cc3)oc1=O)O2 cyanide prediction

CC12CCC3(O)C(C)(C)C(=O)CCC3(C)C1Cc1c(cc(-c3ccc(O)cc3)oc1=O)O2 dna prediction