Aristolochic acid a

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Aristolochic acid a stable oxygenation prediction

Aristolochic acid a unstable oxygenation prediction

Aristolochic acid a dehydrogenation prediction

Aristolochic acid a reduction prediction

Aristolochic acid a hydrolysis prediction

Generation 1

Formaldehyde

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Formaldehyde gsh prediction

Formaldehyde protein prediction

Formaldehyde cyanide prediction

Formaldehyde dna prediction

Generation 2

Select a metabolite to form the next generation.