Aristada

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Aristada stable oxygenation prediction

Aristada unstable oxygenation prediction

Aristada dehydrogenation prediction

Aristada reduction prediction

Aristada hydrolysis prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCCCCCCCCCCC(=O)OCN1C(=O)CCc2ccc(OCCCC=O)cc21 Quinonation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCCCCCCCCCCC(=O)OCN1C(=O)CCC2=CC(=O)C(=O)C=C21 Epoxidation prediction

Generation 3

Select a metabolite to form the next generation.