Tenofovir

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Tenofovir stable oxygenation prediction

Tenofovir unstable oxygenation prediction

Tenofovir dehydrogenation prediction

Tenofovir reduction prediction

Tenofovir hydrolysis prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CC(C=O)OCP(=O)(O)O gsh prediction

CC(C=O)OCP(=O)(O)O protein prediction

CC(C=O)OCP(=O)(O)O cyanide prediction

CC(C=O)OCP(=O)(O)O dna prediction

Generation 2

Select a metabolite to form the next generation.