Amantadine

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Amantadine stable oxygenation prediction

Amantadine unstable oxygenation prediction

Amantadine dehydrogenation prediction

Amantadine reduction prediction

Amantadine hydrolysis prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

O=NC12CC3CC(CC(C3)C1)C2 N-Dealkylation prediction

Generation 2

Select a metabolite to form the next generation.