Altenusin

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Altenusin stable oxygenation prediction

Altenusin unstable oxygenation prediction

Altenusin dehydrogenation prediction

Altenusin reduction prediction

Altenusin hydrolysis prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

COc1cc(O)c(C(=O)O)c(-c2cc(O)c(O)cc2CO)c1 Quinonation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

COc1cc(O)c(C(=O)O)c(C2=CC(=O)C(=O)C=C2CO)c1 Epoxidation prediction

Generation 3

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

COC1=CC(C2=CC(=O)C(=O)C=C2CO)=C(C(=O)O)C2(O)OC12 gsh prediction

COC1=CC(C2=CC(=O)C(=O)C=C2CO)=C(C(=O)O)C2(O)OC12 protein prediction

COC1=CC(C2=CC(=O)C(=O)C=C2CO)=C(C(=O)O)C2(O)OC12 cyanide prediction

COC1=CC(C2=CC(=O)C(=O)C=C2CO)=C(C(=O)O)C2(O)OC12 dna prediction

Generation 4

Select a metabolite to form the next generation.

Showing 5 of 8 metabolites