Adpribose

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Adpribose stable oxygenation prediction

Adpribose unstable oxygenation prediction

Adpribose dehydrogenation prediction

Adpribose reduction prediction

Adpribose hydrolysis prediction

Generation 1

Vidarabine phosphate

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Vidarabine phosphate Quinonation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=C1N=CN=C2C1=NC(=O)N2C1OC(COP(=O)(O)O)C(O)C1O Epoxidation prediction

Generation 3

Select a metabolite to form the next generation.