Substrate
Generation 1
Generation 2

Adp

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Adp stable oxygenation prediction

Adp unstable oxygenation prediction

Adp dehydrogenation prediction

Adp reduction prediction

Adp hydrolysis prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Nc1ncnc2c1ncn2C1OC(COP(=O)([O-])O)C(O)C1O N-Dealkylation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

O=P([O-])(O)OCC1OC(O)C(O)C1O Epoxidation prediction