Substrate
Generation 1

Acronidine

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Acronidine stable oxygenation prediction

Acronidine unstable oxygenation prediction

Acronidine dehydrogenation prediction

Acronidine reduction prediction

Acronidine hydrolysis prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

COc1c2ccoc2nc2cc(O)c3c(c12)C=CC(C)(C)O3 gsh prediction

COc1c2ccoc2nc2cc(O)c3c(c12)C=CC(C)(C)O3 protein prediction

COc1c2ccoc2nc2cc(O)c3c(c12)C=CC(C)(C)O3 cyanide prediction

COc1c2ccoc2nc2cc(O)c3c(c12)C=CC(C)(C)O3 dna prediction