Substrate
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Generation 1
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Generation 2
XenoSite
Carbamazepine
NC(=O)N1c2ccccc2C=Cc2ccccc21
CHEBI
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Description
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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Generation 1
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Dibenzazepine
C1=Cc2ccccc2Nc2ccccc21
CHEBI
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Description
▾
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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Generation 2
Show metabolites
C1=CC2OC23Nc2ccccc2C=CC3=C1
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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stable oxygenation
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unstable oxygenation
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dehydrogenation
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reduction
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hydrolysis
Generation 3
Select a metabolite to form the next generation.
hydroxylation
Probability 0.18
0.18
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hydroxylation
Probability 0.15
0.15
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epoxidation
Probability 0.15
0.15
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hydrogenation
Probability 0.15
0.15
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hydroxylation
Probability 0.14
0.14
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Showing 5 of 79 metabolites
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