Azure c cation

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azure c cation N-Dealkylation prediction

Generation 1

Thionine(1+)

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Thionine(1+) Quinonation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=c1ccc2nc3c(sc-2c1)=CC(=[NH2+])C(=O)C=3 Epoxidation prediction

Generation 3

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=c1ccc2nc3c(sc-2c1)=CC1(NO1)C(=O)C=3 UGT Conjugation prediction