Azilsartan medoxomil anion

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azilsartan medoxomil anion N-Dealkylation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCOc1nc2cccc(C(=O)OCc3oc(=O)oc3C)c2n1Cc1ccc(-c2ccccc2C(N)=NOC(=O)O)cc1 gsh prediction

CCOc1nc2cccc(C(=O)OCc3oc(=O)oc3C)c2n1Cc1ccc(-c2ccccc2C(N)=NOC(=O)O)cc1 protein prediction

CCOc1nc2cccc(C(=O)OCc3oc(=O)oc3C)c2n1Cc1ccc(-c2ccccc2C(N)=NOC(=O)O)cc1 cyanide prediction

CCOc1nc2cccc(C(=O)OCc3oc(=O)oc3C)c2n1Cc1ccc(-c2ccccc2C(N)=NOC(=O)O)cc1 dna prediction

Generation 2

Select a metabolite to form the next generation.