Azabenzimidazole

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azabenzimidazole N-Dealkylation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=C1N=CNC1=CC=CO stable oxygenation prediction

N=C1N=CNC1=CC=CO unstable oxygenation prediction

N=C1N=CNC1=CC=CO dehydrogenation prediction

N=C1N=CNC1=CC=CO reduction prediction

N=C1N=CNC1=CC=CO hydrolysis prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=C(N=CO)C(N)=CC=CO Quinonation prediction