Substrate
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Generation 1
XenoSite
Astemizole
COc1ccc(CCN2CCC(Nc3nc4ccccc4n3Cc3ccc(F)cc3)CC2)cc1
CHEBI
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Description
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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Generation 1
Show metabolites
COc1ccc(CCNCCC(CCO)Nc2nc3ccccc3n2Cc2ccc(F)cc2)cc1
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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gsh
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protein
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cyanide
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dna
Generation 2
Select a metabolite to form the next generation.
glutathionation
Probability 0.02
0.02
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protein
Probability 0.01
0.01
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dna
Probability 0.01
0.01
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cyanide
Probability 0.00
0.00
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