XenoSite
Artemether
COC1OC2OC3(C)CCC4C(C)CCC(C1C)C24OO3
CHEBI
Copy JSON
Description
▾
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%224.358333333333333%22%20r%3D%220.5%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%224.358333333333333%22%20r%3D%220.5%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%223.2472222222222222%22%20r%3D%220.7071067811865476%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.8660254037844386%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%221%22%20fill%3D%22rgb(30%2C94%2C255)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%223.2472222222222222%22%20r%3D%220.5%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%223.2472222222222222%22%20r%3D%220.5%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.7071067811865476%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%220.8660254037844386%22%20fill%3D%22rgb(0%2C200%2C37)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.5%22%20fill%3D%22rgb(197%2C204%2C0)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%222.136111111111111%22%20r%3D%220.5%22%20fill%3D%22rgb(197%2C204%2C0)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%220.7071067811865476%22%20fill%3D%22rgb(197%2C204%2C0)%22%2F%3E%3Ccircle%20cx%3D%221.025%22%20cy%3D%221.025%22%20r%3D%220.5%22%20fill%3D%22rgb(255%2C47%2C0)%22%2F%3E%3Cline%20x1%3D%221.025%22%20y1%3D%221.375%22%20x2%3D%221.025%22%20y2%3D%222.897222222222222%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Cline%20x1%3D%221.025%22%20y1%3D%223.5972222222222223%22%20x2%3D%221.025%22%20y2%3D%225.119444444444445%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Cline%20x1%3D%220.6749999999999999%22%20y1%3D%222.136111111111111%22%20x2%3D%221.375%22%20y2%3D%222.136111111111111%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Cline%20x1%3D%220.6749999999999999%22%20y1%3D%224.358333333333333%22%20x2%3D%221.375%22%20y2%3D%224.358333333333333%22%20stroke%3D%22%23111%22%20stroke-width%3D%220.06%22%2F%3E%3Ctext%20x%3D%221.025%22%20y%3D%221.025%22%20text-anchor%3D%22middle%22%20dominant-baseline%3D%22central%22%20fill%3D%22%23111%22%20stroke%3D%22%23fff%22%20stroke-width%3D%220.18%22%20paint-order%3D%22stroke%22%20font-size%3D%220.72%22%20font-weight%3D%22600%22%20font-family%3D%22system-ui%2Csans-serif%22%3E1.0%3C%2Ftext%3E%3Ctext%20x%3D%221.025%22%20y%3D%223.2472222222222222%22%20text-anchor%3D%22middle%22%20dominant-baseline%3D%22central%22%20fill%3D%22%23111%22%20stroke%3D%22%23fff%22%20stroke-width%3D%220.18%22%20paint-order%3D%22stroke%22%20font-size%3D%220.72%22%20font-weight%3D%22600%22%20font-family%3D%22system-ui%2Csans-serif%22%3E0.5%3C%2Ftext%3E%3Ctext%20x%3D%221.025%22%20y%3D%225.469444444444445%22%20text-anchor%3D%22middle%22%20dominant-baseline%3D%22central%22%20fill%3D%22%23111%22%20stroke%3D%22%23fff%22%20stroke-width%3D%220.18%22%20paint-order%3D%22stroke%22%20font-size%3D%220.72%22%20font-weight%3D%22600%22%20font-family%3D%22system-ui%2Csans-serif%22%3E0.0%3C%2Ftext%3E%3C%2Fsvg%3E){kind=small}
%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2289.0%22%20cy%3D%2286.2%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22130.8%22%20cy%3D%2274.2%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2273.4%22%20cy%3D%2271.2%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2279.8%22%20cy%3D%22129.4%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22115.2%22%20cy%3D%2259.1%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22104.7%22%20cy%3D%22101.3%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2266.9%22%20cy%3D%2290.9%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2257.7%22%20cy%3D%2256.1%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2278.6%22%20cy%3D%2250.0%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2256.7%22%20cy%3D%22111.1%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22151.7%22%20cy%3D%2268.2%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2299.5%22%20cy%3D%2244.0%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22120.4%22%20cy%3D%22116.4%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2295.3%22%20cy%3D%22100.9%22%20style%3D%22fill%3Argb(255%2C255%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2288.5%22%20cy%3D%22114.4%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2296.0%22%20cy%3D%22116.3%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2266.1%22%20cy%3D%22131.6%22%20style%3D%22fill%3Argb(254%2C254%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2281.7%22%20cy%3D%22128.0%22%20style%3D%22fill%3Argb(251%2C252%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22146.5%22%20cy%3D%2289.3%22%20style%3D%22fill%3Argb(248%2C250%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%2272.8%22%20cy%3D%22151.8%22%20style%3D%22fill%3Argb(246%2C249%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22141.3%22%20cy%3D%22110.4%22%20style%3D%22fill%3Argb(233%2C241%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22177.8%22%20cy%3D%22119.4%22%20style%3D%22fill%3Argb(231%2C240%2C255)%22%2F%3E%3Ccircle%20r%3D%229.0%22%20cx%3D%22162.1%22%20cy%3D%22104.3%22%20style%3D%22fill%3Argb(112%2C161%2C255)%22%2F%3E%3C%2Fg%3E%3Cg%20class%3D%22mol_halo%22%20style%3D%22stroke%3Awhite%3Bopacity%3A0.5%3Bstroke-linecap%3Around%3Bstroke-linejoin%3Around%22%3E%3Cg%20id%3D%22mol_halo_xeno_bd38589c1d%22%2F%3E%3Cuse%20href%3D%22%23lines_xeno_bd38589c1d%22%20style%3D%22stroke-width%3A4.0%22%2F%3E%3Cuse%20href%3D%22%23text_xeno_bd38589c1d%22%20style%3D%22stroke-width%3A2.0%22%2F%3E%3C%2Fg%3E%3Cg%20class%3D%22lines%22%20style%3D%22stroke%3A%23000000%3Bstroke-width%3A2.0%3Bstroke-opacity%3A1%3Bstroke-linecap%3Around%3Bstroke-linejoin%3Around%22%3E%3Cg%20id%3D%22lines_xeno_bd38589c1d%22%3E%3Cpath%20class%3D%22bond-0%20atom-0%20atom-1%22%20d%3D%22m181.3%20131.5l-5.7%20-19.6%22%2F%3E%3Cpath%20class%3D%22bond-1%20atom-1%20atom-2%22%20d%3D%22m170.3%20106.4l-20.3%20-5.1%22%2F%3E%3Cpath%20class%3D%22bond-2%20atom-2%20atom-3%22%20d%3D%22m150%20101.3l-13.4%2013.9%22%2F%3E%3Cpath%20class%3D%22bond-3%20atom-3%20atom-4%22%20d%3D%22m128.5%20118.4l-20.3%20-5%22%2F%3E%3Cpath%20class%3D%22bond-4%20atom-4%20atom-5%22%20d%3D%22m108.2%20113.4l-20.4%204.8%22%2F%3E%3Cpath%20class%3D%22bond-5%20atom-5%20atom-6%22%20d%3D%22m82%20123.7l-6.2%2015.9%22%2F%3E%3Cpath%20class%3D%22bond-6%20atom-6%20atom-7%22%20d%3D%22m75.8%20139.6l-6%2024.4%22%2F%3E%3Cpath%20class%3D%22bond-7%20atom-6%20atom-8%22%20d%3D%22m75.8%20139.6l-19.3%20-16%22%2F%3E%3Cpath%20class%3D%22bond-8%20atom-8%20atom-9%22%20d%3D%22m56.5%20123.6l0.4%20-25.1%22%2F%3E%3Cpath%20class%3D%22bond-9%20atom-9%20atom-10%22%20d%3D%22m56.9%2098.5l19.9%20-15.3%22%2F%3E%3Cpath%20class%3D%22bond-10%20atom-10%20atom-11%22%20d%3D%22m76.8%2083.2l-6.9%20-24.1%22%2F%3E%3Cpath%20class%3D%22bond-11%20atom-11%20atom-12%22%20d%3D%22m69.9%2059.1l-24.4%20-6%22%2F%3E%3Cpath%20class%3D%22bond-12%20atom-11%20atom-13%22%20d%3D%22m69.9%2059.1l17.4%20-18.1%22%2F%3E%3Cpath%20class%3D%22bond-13%20atom-13%20atom-14%22%20d%3D%22m87.3%2041l24.4%206%22%2F%3E%3Cpath%20class%3D%22bond-14%20atom-14%20atom-15%22%20d%3D%22m111.7%2047l6.9%2024.2%22%2F%3E%3Cpath%20class%3D%22bond-15%20atom-15%20atom-16%22%20d%3D%22m118.6%2071.2l24.4%206%22%2F%3E%3Cpath%20class%3D%22bond-16%20atom-16%20atom-17%22%20d%3D%22m143%2077.2l17.4%20-18.1%22%2F%3E%3Cpath%20class%3D%22bond-17%20atom-15%20atom-18%22%20d%3D%22m118.6%2071.2l-17.4%2018.1%22%2F%3E%3Cpath%20class%3D%22bond-18%20atom-18%20atom-19%22%20d%3D%22m101.2%2089.3l-9.5%2018.9%22%2F%3E%3Cpath%20class%3D%22bond-19%20atom-19%20atom-20%22%20d%3D%22m89.4%20112.6l-1.8%203.7%22%2F%3E%3Cpath%20class%3D%22bond-20%20atom-16%20atom-2%22%20d%3D%22m143%2077.2l7%2024.1%22%2F%3E%3Cpath%20class%3D%22bond-21%20atom-18%20atom-4%22%20d%3D%22m101.2%2089.3l7%2024.1%22%2F%3E%3Cpath%20class%3D%22bond-22%20atom-20%20atom-6%22%20d%3D%22m85.3%20120.8l-9.5%2018.8%22%2F%3E%3Cpath%20class%3D%22bond-23%20atom-18%20atom-10%22%20d%3D%22m101.2%2089.3l-24.4%20-6.1%22%2F%3E%3Cpath%20d%3D%22m57.4%20124.4l-0.9%20-0.8%20l0%20-1.2%22%2F%3E%3Cpath%20d%3D%22m56.9%2099.8l0%20-1.3%20l1%20-0.8%22%2F%3E%3Cpath%20d%3D%22m86.4%2041.9l0.9%20-0.9%20l1.2%200.3%22%2F%3E%3Cpath%20d%3D%22m110.5%2046.7l1.2%200.3%20l0.3%201.2%22%2F%3E%3C%2Fg%3E%3C%2Fg%3E%3Cg%20class%3D%22text%22%3E%3Cg%20id%3D%22text_xeno_bd38589c1d%22%3E%3Cpath%20class%3D%22atom-1%22%20d%3D%22M%20171.1%20107.4%20Q%20171.1%20105.7%2C%20171.9%20104.7%20Q%20172.8%20103.8%2C%20174.3%20103.8%20Q%20175.9%20103.8%2C%20176.8%20104.7%20Q%20177.6%20105.7%2C%20177.6%20107.4%20Q%20177.6%20109.1%2C%20176.7%20110.1%20Q%20175.9%20111.1%2C%20174.3%20111.1%20Q%20172.8%20111.1%2C%20171.9%20110.1%20Q%20171.1%20109.1%2C%20171.1%20107.4%20M%20174.3%20110.3%20Q%20175.4%20110.3%2C%20176.0%20109.5%20Q%20176.6%20108.8%2C%20176.6%20107.4%20Q%20176.6%20106.0%2C%20176.0%20105.3%20Q%20175.4%20104.6%2C%20174.3%20104.6%20Q%20173.2%20104.6%2C%20172.7%20105.3%20Q%20172.1%20106.0%2C%20172.1%20107.4%20Q%20172.1%20108.8%2C%20172.7%20109.5%20Q%20173.2%20110.3%2C%20174.3%20110.3%20%22%2F%3E%3Cpath%20class%3D%22atom-3%22%20d%3D%22M%20129.3%20119.4%20Q%20129.3%20117.7%2C%20130.1%20116.8%20Q%20131.0%20115.8%2C%20132.5%20115.8%20Q%20134.1%20115.8%2C%20135.0%20116.8%20Q%20135.8%20117.7%2C%20135.8%20119.4%20Q%20135.8%20121.2%2C%20135.0%20122.1%20Q%20134.1%20123.1%2C%20132.5%20123.1%20Q%20131.0%20123.1%2C%20130.1%20122.1%20Q%20129.3%20121.2%2C%20129.3%20119.4%20M%20132.5%20122.3%20Q%20133.6%20122.3%2C%20134.2%20121.6%20Q%20134.8%20120.9%2C%20134.8%20119.4%20Q%20134.8%20118.0%2C%20134.2%20117.3%20Q%20133.6%20116.6%2C%20132.5%20116.6%20Q%20131.5%20116.6%2C%20130.9%20117.3%20Q%20130.3%20118.0%2C%20130.3%20119.4%20Q%20130.3%20120.9%2C%20130.9%20121.6%20Q%20131.5%20122.3%2C%20132.5%20122.3%20%22%2F%3E%3Cpath%20class%3D%22atom-5%22%20d%3D%22M%2080.5%20119.2%20Q%2080.5%20117.5%2C%2081.3%20116.5%20Q%2082.2%20115.6%2C%2083.7%20115.6%20Q%2085.3%20115.6%2C%2086.2%20116.5%20Q%2087.0%20117.5%2C%2087.0%20119.2%20Q%2087.0%20120.9%2C%2086.1%20121.9%20Q%2085.3%20122.9%2C%2083.7%20122.9%20Q%2082.2%20122.9%2C%2081.3%20121.9%20Q%2080.5%20120.9%2C%2080.5%20119.2%20M%2083.7%20122.1%20Q%2084.8%20122.1%2C%2085.4%20121.3%20Q%2086.0%20120.6%2C%2086.0%20119.2%20Q%2086.0%20117.8%2C%2085.4%20117.1%20Q%2084.8%20116.4%2C%2083.7%20116.4%20Q%2082.7%20116.4%2C%2082.1%20117.1%20Q%2081.5%20117.8%2C%2081.5%20119.2%20Q%2081.5%20120.6%2C%2082.1%20121.3%20Q%2082.7%20122.1%2C%2083.7%20122.1%20%22%2F%3E%3Cpath%20class%3D%22atom-19%22%20d%3D%22M%2086.2%20112.6%20Q%2086.2%20110.9%2C%2087.0%20109.9%20Q%2087.9%20109.0%2C%2089.4%20109.0%20Q%2091.0%20109.0%2C%2091.9%20109.9%20Q%2092.7%20110.9%2C%2092.7%20112.6%20Q%2092.7%20114.3%2C%2091.9%20115.3%20Q%2091.0%20116.3%2C%2089.4%20116.3%20Q%2087.9%20116.3%2C%2087.0%20115.3%20Q%2086.2%20114.3%2C%2086.2%20112.6%20M%2089.4%20115.5%20Q%2090.5%20115.5%2C%2091.1%20114.8%20Q%2091.7%20114.0%2C%2091.7%20112.6%20Q%2091.7%20111.2%2C%2091.1%20110.5%20Q%2090.5%20109.8%2C%2089.4%20109.8%20Q%2088.4%20109.8%2C%2087.8%20110.5%20Q%2087.2%20111.2%2C%2087.2%20112.6%20Q%2087.2%20114.0%2C%2087.8%20114.8%20Q%2088.4%20115.5%2C%2089.4%20115.5%20%22%2F%3E%3Cpath%20class%3D%22atom-20%22%20d%3D%22M%2084.3%20116.3%20Q%2084.3%20114.6%2C%2085.1%20113.7%20Q%2086.0%20112.7%2C%2087.6%20112.7%20Q%2089.1%20112.7%2C%2090.0%20113.7%20Q%2090.8%20114.6%2C%2090.8%20116.3%20Q%2090.8%20118.0%2C%2090.0%20119.0%20Q%2089.1%20120.0%2C%2087.6%20120.0%20Q%2086.0%20120.0%2C%2085.1%20119.0%20Q%2084.3%20118.1%2C%2084.3%20116.3%20M%2087.6%20119.2%20Q%2088.7%20119.2%2C%2089.2%20118.5%20Q%2089.8%20117.7%2C%2089.8%20116.3%20Q%2089.8%20114.9%2C%2089.2%20114.2%20Q%2088.7%20113.5%2C%2087.6%20113.5%20Q%2086.5%20113.5%2C%2085.9%20114.2%20Q%2085.3%20114.9%2C%2085.3%20116.3%20Q%2085.3%20117.8%2C%2085.9%20118.5%20Q%2086.5%20119.2%2C%2087.6%20119.2%20%22%2F%3E%3C%2Fg%3E%3C!--%20END%20OF%20HEADER%20--%3E%3C%2Fg%3E%3Cg%20class%3D%22overlay%22%3E%3Cg%20id%3D%22overlay_xeno_bd38589c1d%22%2F%3E%3C%2Fg%3E%3Cscript%20type%3D%22application%2Fjson%22%3E%7B%26quot%3Bcoords%26quot%3B%3A%20%5B%5B181.3%2C%20131.5%5D%2C%20%5B174.3%2C%20107.4%5D%2C%20%5B150.0%2C%20101.3%5D%2C%20%5B132.5%2C%20119.4%5D%2C%20%5B108.2%2C%20113.4%5D%2C%20%5B83.7%2C%20119.2%5D%2C%20%5B75.8%2C%20139.6%5D%2C%20%5B69.8%2C%20164.0%5D%2C%20%5B56.5%2C%20123.6%5D%2C%20%5B56.9%2C%2098.5%5D%2C%20%5B76.8%2C%2083.2%5D%2C%20%5B69.9%2C%2059.1%5D%2C%20%5B45.5%2C%2053.1%5D%2C%20%5B87.3%2C%2041.0%5D%2C%20%5B111.7%2C%2047.0%5D%2C%20%5B118.6%2C%2071.2%5D%2C%20%5B143.0%2C%2077.2%5D%2C%20%5B160.4%2C%2059.1%5D%2C%20%5B101.2%2C%2089.3%5D%2C%20%5B89.4%2C%20112.6%5D%2C%20%5B87.6%2C%20116.3%5D%5D%2C%20%26quot%3Bscale%26quot%3B%3A%2020%7D%3C%2Fscript%3E%3C%2Fsvg%3E)