Amp morpholidate

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Amp morpholidate N-Dealkylation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Nc1ncnc2c1ncn2C1OC(COP(=O)(O)NCCOCCO)C(O)C1O stable oxygenation prediction

Nc1ncnc2c1ncn2C1OC(COP(=O)(O)NCCOCCO)C(O)C1O unstable oxygenation prediction

Nc1ncnc2c1ncn2C1OC(COP(=O)(O)NCCOCCO)C(O)C1O dehydrogenation prediction

Nc1ncnc2c1ncn2C1OC(COP(=O)(O)NCCOCCO)C(O)C1O reduction prediction

Nc1ncnc2c1ncn2C1OC(COP(=O)(O)NCCOCCO)C(O)C1O hydrolysis prediction

Generation 2

Adenosine 5'-phosphoramidate

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Adenosine 5'-phosphoramidate gsh prediction

Adenosine 5'-phosphoramidate protein prediction

Adenosine 5'-phosphoramidate cyanide prediction

Adenosine 5'-phosphoramidate dna prediction