Substrate
Generation 1
Generation 2

Acivicin

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Acivicin N-Dealkylation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

O=C(O)C(=O)C1CC(Cl)=NO1 Epoxidation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

O=C(O)C(=O)C1CC2(Cl)ON2O1 Quinonation prediction