Nalidixic acid

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Nalidixic acid N-Dealkylation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Cc1ccc2c(=O)c(C(=O)O)c[nH]c2n1 Epoxidation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CC12C=Cc3c([nH]cc(C(=O)O)c3=O)N1O2 gsh prediction

CC12C=Cc3c([nH]cc(C(=O)O)c3=O)N1O2 protein prediction

CC12C=Cc3c([nH]cc(C(=O)O)c3=O)N1O2 cyanide prediction

CC12C=Cc3c([nH]cc(C(=O)O)c3=O)N1O2 dna prediction

Generation 3

Select a metabolite to form the next generation.