Nalidixic acid

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Nalidixic acid N-Dealkylation prediction

Generation 1

(11c)acetic acid

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

(11c)acetic acid stable oxygenation prediction

(11c)acetic acid unstable oxygenation prediction

(11c)acetic acid dehydrogenation prediction

(11c)acetic acid reduction prediction

(11c)acetic acid hydrolysis prediction

Generation 2

A polyvinyl alcohol

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

A polyvinyl alcohol UGT Conjugation prediction

Generation 3

Select a metabolite to form the next generation.

glucuronidation
1.00