Substrate
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Generation 1
XenoSite
Abacavir carboxylate
Nc1nc(NC2CC2)c2ncn(C3C=CC(C(=O)O)C3)c2n1
CHEBI
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Description
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
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Generation 1
Show metabolites
O=C1C=CC(C(=O)O)C1
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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stable oxygenation
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unstable oxygenation
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dehydrogenation
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reduction
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hydrolysis
Generation 2
Select a metabolite to form the next generation.
hydrogenation
Probability 0.49
0.49
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hydrogenation
Probability 0.08
0.08
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3-ketocyclopentanecarboxylic acid
hydroxylation
Probability 0.07
0.07
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hydroxylation
Probability 0.06
0.06
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epoxidation
Probability 0.05
0.05
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Showing 5 of 34 metabolites
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