Substrate
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Generation 1
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Generation 2
XenoSite
Troglitazone
Cc1c(C)c2c(c(C)c1O)CCC(C)(COc1ccc(CC3SC(=O)NC3=O)cc1)O2
CHEBI
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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Generation 1
Show metabolites
CC1=C(O)C2(C)OC2(C)C2=C1CCC(C)(COc1ccc(CC3SC(=O)NC3=O)cc1)O2
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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Generation 2
Show metabolites
O=C1C=CC(=CC2SC(=O)NC2=O)C=C1
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
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gsh
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protein
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cyanide
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dna
Generation 3
Select a metabolite to form the next generation.
protein
Probability 0.46
0.46
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dna
Probability 0.42
0.42
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glutathionation
Probability 0.22
0.22
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cyanide
Probability 0.00
0.00
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