Substrate
/
Generation 1
XenoSite
Carbamazepine
NC(=O)N1c2ccccc2C=Cc2ccccc21
CHEBI
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Description
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
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Generation 1
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Carbamazepine epoxide
NC(=O)N1c2ccccc2C2OC2c2ccccc21
CHEBI
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Description
▾
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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stable oxygenation
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unstable oxygenation
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dehydrogenation
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reduction
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hydrolysis
Generation 2
Select a metabolite to form the next generation.
hydroxylation
Probability 0.17
0.17
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hydroxylation
Probability 0.15
0.15
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dealkylation
Probability 0.14
0.14
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dealkylation
Probability 0.14
0.14
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(10<i>r</i>,11<i>r</i>)-dihydroxy-10,11-dihydrocarbamazepine
hydroxylation
Probability 0.06
0.06
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Showing 5 of 67 metabolites
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