Azabenzimidazole

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azabenzimidazole Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

C1=Nc2nc[nH]c2C2OC12 N-Dealkylation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NC1=C(N=C=O)N=CC2OC12 stable oxygenation prediction

NC1=C(N=C=O)N=CC2OC12 unstable oxygenation prediction

NC1=C(N=C=O)N=CC2OC12 dehydrogenation prediction

NC1=C(N=C=O)N=CC2OC12 reduction prediction

NC1=C(N=C=O)N=CC2OC12 hydrolysis prediction

Generation 3

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NC1=C(N=C=O)N=CC(O)C1O UGT Conjugation prediction

Generation 4

Select a metabolite to form the next generation.