Substrate
/
Generation 1
XenoSite
Apremilast
CCOc1cc(C(CS(C)(=O)=O)N2C(=O)c3cccc(NC(C)=O)c3C2=O)ccc1OC
CHEBI
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Description
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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Generation 1
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CCOC12OC1C(C(CS(C)(=O)=O)N1C(=O)c3cccc(NC(C)=O)c3C1=O)=CC=C2OC
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
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Generation 2
Select a metabolite to form the next generation.
n dealkylation
Probability 0.67
0.67
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N-(1,3-dioxo-4-isoindolyl)acetamide
n dealkylation
Probability 0.67
0.67
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n dealkylation
Probability 0.67
0.67
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n dealkylation
Probability 0.42
0.42
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(11c)acetic acid
n dealkylation
Probability 0.42
0.42
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Showing 5 of 9 metabolites
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