Alogliptin

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Alogliptin Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Cn1c(=O)cc(N2CCCC(N)C2)n(CC23C=CC=CC2(C#N)O3)c1=O stable oxygenation prediction

Cn1c(=O)cc(N2CCCC(N)C2)n(CC23C=CC=CC2(C#N)O3)c1=O unstable oxygenation prediction

Cn1c(=O)cc(N2CCCC(N)C2)n(CC23C=CC=CC2(C#N)O3)c1=O dehydrogenation prediction

Cn1c(=O)cc(N2CCCC(N)C2)n(CC23C=CC=CC2(C#N)O3)c1=O reduction prediction

Cn1c(=O)cc(N2CCCC(N)C2)n(CC23C=CC=CC2(C#N)O3)c1=O hydrolysis prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Cn1c(=O)cc(N2CCCC(N)C2)n(CO)c1=O gsh prediction

Cn1c(=O)cc(N2CCCC(N)C2)n(CO)c1=O protein prediction

Cn1c(=O)cc(N2CCCC(N)C2)n(CO)c1=O cyanide prediction

Cn1c(=O)cc(N2CCCC(N)C2)n(CO)c1=O dna prediction