Adp

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Adp Epoxidation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NC12N=CN=C3N(C4OC(COP(=O)([O-])OP(=O)([O-])[O-])C(O)C4O)C=NC31O2 N-Dealkylation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

N=CN=C1N(C2OC(COP(=O)([O-])OP(=O)([O-])[O-])C(O)C2O)C=NC12OC2(N)O UGT Conjugation prediction

Generation 3

Select a metabolite to form the next generation.