Benazeprilat

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Benazeprilat Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

O=C1C=CC2=[N+](CC(=O)O)C(=O)C(NC(CCc3ccccc3)C(=O)O)CCC2=C1 N-Dealkylation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NC1CCC2=CC(=O)C=CC2=[N+](CC(=O)O)C1=O Epoxidation prediction

Generation 3

epoxidation · 0.04

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

NC1CCC2=CC(=O)C3OC3C2=[N+](CC(=O)O)C1=O