Balsalazide

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Balsalazide Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

O=C(O)CCNC(=O)C1=CC=C(N=Nc2ccc(O)c(C(=O)O)c2)C(=O)C1=O UGT Conjugation prediction

Generation 2

glucuronidation · 0.08

*OC(=O)c1cc(N=NC2=CC=C(C(=O)NCCC(=O)O)C(=O)C2=O)ccc1O |$GlcA;;;;;;;;;;;;;;;;;;;;;;;;;;;;$|