Balsalazide

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Balsalazide Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

O=C(O)CCNC(=O)c1ccc(N=NC2=CC(C(=O)O)=C(O)C(=O)C2=O)cc1 UGT Conjugation prediction

Generation 2

glucuronidation · 0.10

*OC(=O)C1=C(O)C(=O)C(=O)C(N=Nc2ccc(C(=O)NCCC(=O)O)cc2)=C1 |$GlcA;;;;;;;;;;;;;;;;;;;;;;;;;;;;$|