Azodopa

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azodopa Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN(C)CCc1ccccc1N=NC1=CC(=O)C(=O)C=C1 N-Dealkylation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CNCCc1ccccc1N=NC1=CC(=O)C(=O)C=C1 stable oxygenation prediction

CNCCc1ccccc1N=NC1=CC(=O)C(=O)C=C1 unstable oxygenation prediction

CNCCc1ccccc1N=NC1=CC(=O)C(=O)C=C1 dehydrogenation prediction

CNCCc1ccccc1N=NC1=CC(=O)C(=O)C=C1 reduction prediction

CNCCc1ccccc1N=NC1=CC(=O)C(=O)C=C1 hydrolysis prediction

Generation 3

Formaldehyde

dealkylation · 0.61

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Formaldehyde