Azodopa

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Azodopa Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN(C)CCc1ccccc1N=NC1=CC(=O)C(O)=CC1=O Epoxidation prediction

Generation 2

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN(C)CCc1ccccc1N=NC1=CC(=O)C2(O)OC2C1=O UGT Conjugation prediction

Generation 3

glucuronidation · 0.95

*OC12OC1C(=O)C(N=Nc1ccccc1CCN(C)C)=CC2=O |$GlcA;;;;;;;;;;;;;;;;;;;;;;;$|