Arenamide a

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Arenamide a Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCCCCCC(C)C1CC(=O)NCC(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CC2=CC=CC(=O)C2=O)C(=O)O1 N-Dealkylation prediction

Generation 2

dealkylation · 0.48

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CCCCCCC(C)C(CC(=O)NCC(N)=O)OC(=O)C(CC1=CC=CC(=O)C1=O)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(=O)C(C)C