Substrate
/
Generation 1
/
Generation 2
XenoSite
Tenofovir
CC(Cn1cnc2c(N)ncnc21)OCP(=O)(O)O
CHEBI
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Description
▾
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
Generation 1
Show metabolites
CC(C[N+]1=c2ncnc(N)c2=NC1=O)OCP(=O)(O)O
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Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
i
About this model
Generation 2
Show metabolites
Nc1ncnc2c1=NC(=O)N=2
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dealkylation · 0.41
Phase 1
Reactivity
Epoxidation
Quinonation
N-Dealkylation
UGT Conjugation
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![CC(C[N+]1=c2ncnc(N)c2=NC1=O)OCP(=O)(O)O N-Dealkylation 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