Alogliptin

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

Alogliptin Quinonation prediction

Generation 1

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN1C(=O)C(=O)C(=[N+]2CCCC(N)C2)N(Cc2ccccc2C#N)C1=O Epoxidation prediction

Generation 2

epoxidation · 0.02

Phase 1 Reactivity Epoxidation Quinonation N-Dealkylation UGT Conjugation

CN1C(=O)C(=O)C(=[N+]2CCCC(N)C2)N(CC2=C(C#N)C3OC3C=C2)C1=O